… disease: a buildup of double-stranded breaks (DSBs) in the DNA of neurons and the inflammatory behavior of microglia, … actively trigger an inflammatory response to their genomic damage. Neurons have not been known to signal the brain’s … also lost their ability to express a standard marker of neuronal identity. Welch realized there seemed to be stages …
… they found dramatic reductions in neurodegeneration and DNAdamage in the brain. These mice also showed improvements in … Cdk5 , neurodegeneration , Neuroimmune interactions , NeuronalDNAdamage , dementia Print Share In the media The …
… cells, such as levels of RNA which is transcribed from DNA, so that the cell’s functions and roles of in the biology … and metabolism Metabolic stress and protein folding DNAdamage and cellular senescence (aging) Interactions with … Article Neuroimmune interactions , lipid metabolism , NeuronalDNAdamage , neurodegeneration Print Share Related …
… Breaking DNA in health and disease By studying the roots of memory … In studying mice modeling Alzheimer’s, Tsai’s lab observed DNAdamage in neurons, including an accumulation of …
… biological tissue, allowing them to visualize proteins, DNA, and other molecules within cells, and to map the … studied unless steps are taken to preserve the tissue from damage. Chung and other researchers have previously developed … blocks of proteins), as well as other molecules such as DNA and RNA. The flexible backbone allows the epoxides to …